CD53 / Janelia Fluor 585 / 425514

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: FAB4624JF585 (View supplier product page)
Size 100 μl
Price $529.00
Antigen CD53
Clone 425514
Host Mouse
Isotype IgG2a
Conjugate Janelia Fluor 585
Target Species Human
Applications FC, CyTOF
Description CD53 Antibody (425514) [Janelia Fluor® 585]
About CD53 and Janelia Fluor 585
CD53 The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein that is known to complex with integrins. It contributes to the transduction of CD2-generated signals in T cells and natural killer cells and has been suggested to play a role in growth regulation. Familial deficiency of this gene has been linked to an immunodeficiency associated with recurrent infectious diseases caused by bacteria, fungi and viruses. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2016]
Janelia Fluor 585 Janelia Fluor® 585 was developed at the Janelia Campus of the Howard Hughes Medical Institute but is commercialized by other vendors. The Janelia Fluor®s family is unique in that the fluorophores are cell-permeable and are available in photoactivatable forms. These fluorophores were developed for super-resolution microscopy (STED, PALM and STORM) and live-cell microscopy in the HaloTag and SNAP-tag versions. Janelia Fluor® 585 has an excitation peak at 585 nm and an emission peak at 609 nm.
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Janelia Fluor 585 Excitation and Emission Spectra