CD45 / PE-ATTO 594 / 998209

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: FAB14301PEATT594 (View supplier product page)
Size 100 μl
Price $579.00
Antigen CD45
Clone 998209
Host Mouse
Isotype IgG1
Conjugate PE-ATTO 594
Target Species Human
Applications FC
Description CD45 Antibody (998209) [PE/Atto594]
About CD45 and PE-ATTO 594
CD45 The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitosis, and oncogenic transformation. This PTP contains an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus is classified as a receptor type PTP. This PTP has been shown to be an essential regulator of T- and B-cell antigen receptor signaling. It functions through either direct interaction with components of the antigen receptor complexes, or by activating various Src family kinases required for the antigen receptor signaling. This PTP also suppresses JAK kinases, and thus functions as a regulator of cytokine receptor signaling. Alternatively spliced transcripts variants of this gene, which encode distinct isoforms, have been reported. [provided by RefSeq, Jun 2012]
PE-ATTO 594 PE-ATTO 594 from ATTO-TEC has an excitation peak at 565 nm and an emission peak at 627 nm. It is an alternative to PE-Dazzle 594, PE-Alexa 610, PE-eFluor™ 610 and PE-CF®594.
Citations
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Reviews & Ratings
PE-ATTO 594 Excitation and Emission Spectra