CD44 / CoraFluor-1 / SPM544

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NBP2-34420CL1 (View supplier product page)
Size 100 μl
Price $1,029.00
Antigen CD44
Clone SPM544
Host Mouse
Isotype IgG2a κ
Conjugate CoraFluor-1
Target Species Baboon, Human, Monkey
Applications IHC, WB, IHC-P, CyTOF, ICC, IF
Description CD44 Antibody (SPM544) [CoraFluor™ 1]
About CD44 and CoraFluor-1
CD44 The protein encoded by this gene is a cell-surface glycoprotein involved in cell-cell interactions, cell adhesion and migration. It is a receptor for hyaluronic acid (HA) and can also interact with other ligands, such as osteopontin, collagens, and matrix metalloproteinases (MMPs). This protein participates in a wide variety of cellular functions including lymphocyte activation, recirculation and homing, hematopoiesis, and tumor metastasis. Transcripts for this gene undergo complex alternative splicing that results in many functionally distinct isoforms, however, the full length nature of some of these variants has not been determined. Alternative splicing is the basis for the structural and functional diversity of this protein, and may be related to tumor metastasis. [provided by RefSeq, Jul 2008]
CoraFluor-1 CoraFluors are luminescent terbium complexes developed by the Mazitschek lab at the Massachusetts General Hospital and Harvard University. The high brightness, long emission lifetimes (> 1 ms) and excellent stability of CoraFluors make them well-suited tools for biomedical assay applications, including homogenous and intracellular time-gated fluorescent measurements (e.g., homogenous and intracellular TR-FRET assays). CoraFluors can be excited with near-UV light and exhibit several narrow emission bands (490 nm, 545 nm, 585 nm, 620 nm), providing compatibility with a broad range of organic fluorophores and fluorescent proteins in TR-FRET experiments.
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CoraFluor-1 Excitation and Emission Spectra