CD38 / DyLight 755 / daratumumab

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NBP3-28193IR (View supplier product page)
Size 100 μl
Price $379.00
Antigen CD38
Clone daratumumab
Host Human
Isotype IgG1
Conjugate DyLight 755
Target Species Human
Applications FC, ELISA, Functional
Description CD38 Antibody (daratumumab) [DyLight 755]
About CD38 and DyLight 755
CD38 The protein encoded by this gene is a non-lineage-restricted, type II transmembrane glycoprotein that synthesizes and hydrolyzes cyclic adenosine 5'-diphosphate-ribose, an intracellular calcium ion mobilizing messenger. The release of soluble protein and the ability of membrane-bound protein to become internalized indicate both extracellular and intracellular functions for the protein. This protein has an N-terminal cytoplasmic tail, a single membrane-spanning domain, and a C-terminal extracellular region with four N-glycosylation sites. Crystal structure analysis demonstrates that the functional molecule is a dimer, with the central portion containing the catalytic site. It is used as a prognostic marker for patients with chronic lymphocytic leukemia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2015]
DyLight 755 DyLight™ 755 has an excitation peak of 754 nm and an emission peak of 776 nm and is spectrally similar to Alexa Fluor™ 750. DyLight™ 755 is most commonly used in fluorescence micrscopy.
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DyLight 755 Excitation and Emission Spectra