CD11b / CoraFluor-1 / M1/70.15

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NB600-1327CL1 (View supplier product page)
Size 100 μl
Price $899.00
Antigen CD11b
Clone M1/70.15
Host Rat
Isotype IgG2b λ
Conjugate CoraFluor-1
Target Species Human, Mouse, Rabbit
Applications FC, IHC, IP, IHC-P, IHC-Fr, CyTOF, ICC, IF
Description CD11b Antibody (M1/70.15) [CoraFluor™ 1]
About CD11b and CoraFluor-1
CD11b This gene encodes the integrin alpha M chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as macrophage receptor 1 ('Mac-1'), or inactivated-C3b (iC3b) receptor 3 ('CR3'). The alpha M beta 2 integrin is important in the adherence of neutrophils and monocytes to stimulated endothelium, and also in the phagocytosis of complement coated particles. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009]
CoraFluor-1 CoraFluors are luminescent terbium complexes developed by the Mazitschek lab at the Massachusetts General Hospital and Harvard University. The high brightness, long emission lifetimes (> 1 ms) and excellent stability of CoraFluors make them well-suited tools for biomedical assay applications, including homogenous and intracellular time-gated fluorescent measurements (e.g., homogenous and intracellular TR-FRET assays). CoraFluors can be excited with near-UV light and exhibit several narrow emission bands (490 nm, 545 nm, 585 nm, 620 nm), providing compatibility with a broad range of organic fluorophores and fluorescent proteins in TR-FRET experiments.
Citations
Additional
Sources
Reviews & Ratings
Submit a Review

CoraFluor-1 Excitation and Emission Spectra