CCR9 / PE-Cy5.5 / 242503

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: FAB2160PECY55 (View supplier product page)
Size 100 μl
Price $569.00
Antigen CCR9
Clone 242503
Host Rat
Isotype IgG2b
Conjugate PE-Cy5.5
Target Species Mouse
Applications FC
Description CCR9 Antibody (242503) [PE/Cy5.5]
About CCR9 and PE-Cy5.5
CCR9 The protein encoded by this gene is a G protein-coupled receptor with seven transmembrane domains that belongs to the beta chemokine receptor family. Chemokines and their receptors are key regulators of thymocyte migration and maturation in normal and inflammation conditions. This gene is differentially expressed in T lymphocytes of the small intestine and colon, and its interaction with chemokine 25 contributes to intestinal intra-epithelial lymphocyte homing to the small intestine. This suggests a role for this gene in directing immune responses to different segments of the gastrointestinal tract. This gene and its exclusive ligand, chemokine 25, are overexpressed in a variety of malignant tumors and are closely associated with tumor proliferation, apoptosis, invasion, migration and drug resistance. This gene maps to the chemokine receptor gene cluster. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2020]
PE-Cy5.5 PE-Cyanine®5.5 (PE-Cy5.5) is a red-emitting tandem fluorophore that combines phycoerythrin (PE) and Cy5.5. The donor molecule, PE can be excited by the 488-nm blue, 532-nm green, or 561-nm yellow-green laser and and transfers energy to the acceptor molecule, Cy5.5. PE-Cy5.5 has an excitation peak at 496 nm and an emission peak at 695 nm.
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PE-Cy5.5 Excitation and Emission Spectra