CD192 / CoraFluor-1 / 2D8

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NBP2-35333CL1 (View supplier product page)
Size 100 μl
Price $899.00
Antigen CD192
Clone 2D8
Host Mouse
Isotype IgG2b λ
Conjugate CoraFluor-1
Target Species Human
Applications IHC, WB, IHC-P
Description CCR2 Antibody (2D8) [CoraFluor™ 1]
About CD192 and CoraFluor-1
CD192 The protein encoded by this gene is a receptor for monocyte chemoattractant protein-1, a chemokine which specifically mediates monocyte chemotaxis. Monocyte chemoattractant protein-1 is involved in monocyte infiltration in inflammatory diseases such as rheumatoid arthritis as well as in the inflammatory response against tumors. The encoded protein mediates agonist-dependent calcium mobilization and inhibition of adenylyl cyclase. This protein can also be a coreceptor with CD4 for HIV-1 infection. This gene is located in the chemokine receptor gene cluster region of chromosome 3. [provided by RefSeq, Aug 2017]
CoraFluor-1 CoraFluors are luminescent terbium complexes developed by the Mazitschek lab at the Massachusetts General Hospital and Harvard University. The high brightness, long emission lifetimes (> 1 ms) and excellent stability of CoraFluors make them well-suited tools for biomedical assay applications, including homogenous and intracellular time-gated fluorescent measurements (e.g., homogenous and intracellular TR-FRET assays). CoraFluors can be excited with near-UV light and exhibit several narrow emission bands (490 nm, 545 nm, 585 nm, 620 nm), providing compatibility with a broad range of organic fluorophores and fluorescent proteins in TR-FRET experiments.
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CoraFluor-1 Excitation and Emission Spectra