LIF R alpha / Unconjugated / 32953
LIF R alpha / Unconjugated / 32953
Citations:
(2)
Product Details
Supplier | R&D Systems | |
---|---|---|
Catalog #: | MAB249 (View supplier product page) | |
Size | 500 μg | |
Price | $559.00 | |
Antigen | LIF R alpha | |
Clone | 32953 | |
Host | Mouse | |
Isotype | IgG1 | |
Conjugate | Unconjugated | |
Target Species | Human | |
Applications | FC, WB, CyTOF | |
Description | Human LIFR alpha Antibody |
About LIF R alpha and Purified
LIF R alpha | This gene encodes a protein that belongs to the type I cytokine receptor family. This protein combines with a high-affinity converter subunit, gp130, to form a receptor complex that mediates the action of the leukemia inhibitory factor, a polyfunctional cytokine that is involved in cellular differentiation, proliferation and survival in the adult and the embryo. Mutations in this gene cause Schwartz-Jampel syndrome type 2, a disease belonging to the group of the bent-bone dysplasias. A translocation that involves the promoter of this gene, t(5;8)(p13;q12) with the pleiomorphic adenoma gene 1, is associated with salivary gland pleiomorphic adenoma, a common type of benign epithelial tumor of the salivary gland. Multiple splice variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jun 2018] |
---|
Citations
PMID 12372336 | ||
---|---|---|
PMID 28533357 | ||
Additional Sources |
![]() |
Reviews & Ratings
Purified Excitation and Emission Spectra
$559.00
Supplier Page
Supplier Page