Angiopoietin-2 / DyLight 488 / MEDI3617

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NBP3-28825G (View supplier product page)
Size 100 μl
Price $379.00
Antigen Angiopoietin-2
Clone MEDI3617
Host Human
Isotype IgG2
Conjugate DyLight 488
Target Species Human
Applications FC, ELISA, Functional
Description Angiopoietin-2 Antibody (MEDI3617) [DyLight 488]
About Angiopoietin-2 and DyLight 488
Angiopoietin-2 This gene belongs to the angiopoietin family of growth factors. The protein encoded by this gene is an antagonist of angiopoietin 1, and both angiopoietin 1 and angiopoietin 2 are ligands for the endothelial TEK receptor tyrosine kinase. Angiopoietin 2 is upregulated in multiple inflammatory diseases and is implicated in the direct control of inflammation-related signaling pathways. The encoded protein affects angiogenesis during embryogenesis and tumorigenesis, disrupts the vascular remodeling ability of angiopoietin 1, and may induce endothelial cell apoptosis. This gene serves a prognostic biomarker for acute respiratory distress syndrome. [provided by RefSeq, Aug 2020]
DyLight 488 DyLight™ 488 has an excitation peak at 493 nm and an emission peak at 518 nm and is spectrally similar to Alexa Fluor™ 488, fluorescein and FITC. DyLight™ 488 is most commonly used in flow cytometery, and fluorescence microscopy applications.
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DyLight 488 Excitation and Emission Spectra