Activin RIIB / DyLight 755 / Oxford Brookes U. patent anti-Activin Beta-B

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NBP3-28868IR (View supplier product page)
Size 100 μl
Price $379.00
Antigen Activin RIIB
Clone Oxford Brookes U. patent anti-Activin Beta-B
Host Human
Isotype IgG1
Conjugate DyLight 755
Target Species Human
Applications FC, ELISA, Functional
Description Activin RIIB Antibody (Oxford Brookes U. patent anti-Activin Beta-B) [DyLight 755]
About Activin RIIB and DyLight 755
Activin RIIB Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I (I and IB) and two type II (II and IIB) receptors. These receptors are all transmembrane proteins, composed of a ligand-binding extracellular domain with cysteine-rich region, a transmembrane domain, and a cytoplasmic domain with predicted serine/threonine specificity. Type I receptors are essential for signaling; and type II receptors are required for binding ligands and for expression of type I receptors. Type I and II receptors form a stable complex after ligand binding, resulting in phosphorylation of type I receptors by type II receptors. Type II receptors are considered to be constitutively active kinases. This gene encodes activin A type IIB receptor, which displays a 3- to 4-fold higher affinity for the ligand than activin A type II receptor. [provided by RefSeq, Jul 2008]
DyLight 755 DyLight™ 755 has an excitation peak of 754 nm and an emission peak of 776 nm and is spectrally similar to Alexa Fluor™ 750. DyLight™ 755 is most commonly used in fluorescence micrscopy.
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DyLight 755 Excitation and Emission Spectra