SET / Unconjugated / Polyclonal

Product Details
Supplier Bethyl Laboratories
Catalog #: IHC-00645 (View supplier product page)
Size 5 µg
Price $459.00
Antigen SET
Clone Polyclonal
Host Rabbit
Isotype IgG
Conjugate Unconjugated
Target Species Human
Applications IHC
Description Rabbit anti-SET IHC Antibody, Affinity Purified
About SET and Purified
SET The protein encoded by this gene inhibits acetylation of nucleosomes, especially histone H4, by histone acetylases (HAT). This inhibition is most likely accomplished by masking histone lysines from being acetylated, and the consequence is to silence HAT-dependent transcription. The encoded protein is part of a complex localized to the endoplasmic reticulum but is found in the nucleus and inhibits apoptosis following attack by cytotoxic T lymphocytes. This protein can also enhance DNA replication of the adenovirus genome. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]
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Purified Excitation and Emission Spectra