REST / Unconjugated / Polyclonal

Product Details
Supplier Bethyl Laboratories
Catalog #: IHC-00141-T (View supplier product page)
Size 2.5 µg
Price $121.00
Antigen REST
Clone Polyclonal
Host Rabbit
Isotype IgG
Conjugate Unconjugated
Target Species Human
Applications IHC
Description Rabbit anti-REST IHC Antibody, Affinity Purified
About REST and Purified
REST This gene was initially identified as a transcriptional repressor that represses neuronal genes in non-neuronal tissues. However, depending on the cellular context, this gene can act as either an oncogene or a tumor suppressor. The encoded protein is a member of the Kruppel-type zinc finger transcription factor family. It represses transcription by binding a DNA sequence element called the neuron-restrictive silencer element. The protein is also found in undifferentiated neuronal progenitor cells and it is thought that this repressor may act as a master negative regulator of neurogenesis. Alternatively spliced transcript variants have been described. [provided by RefSeq, May 2018]
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Purified Excitation and Emission Spectra