CCNT1 / Unconjugated / Polyclonal

Product Details
Supplier Bethyl Laboratories
Catalog #: A303-499A-T (View supplier product page)
Size 2 µg
Price $121.00
Antigen CCNT1
Clone Polyclonal
Host Rabbit
Isotype IgG
Conjugate Unconjugated
Target Species Human
Applications WB, IP, IHC
Description Rabbit anti-Cyclin T1 Antibody, Affinity Purified
About CCNT1 and Purified
CCNT1 This gene encodes a member of the highly conserved cyclin C subfamily. The encoded protein tightly associates with cyclin-dependent kinase 9, and is a major subunit of positive transcription elongation factor b (p-TEFb). In humans, there are multiple forms of positive transcription elongation factor b, which may include one of several different cyclins along with cyclin-dependent kinase 9. The complex containing the encoded cyclin and cyclin-dependent kinase 9 acts as a cofactor of human immunodeficiency virus type 1 (HIV-1) Tat protein, and is both necessary and sufficient for full activation of viral transcription. This cyclin and its kinase partner are also involved in triggering transcript elongation through phosphorylation of the carboxy-terminal domain of the largest RNA polymerase II subunit. Overexpression of this gene is implicated in tumor growth. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2013]
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Purified Excitation and Emission Spectra