Brg1 / Unconjugated / Polyclonal

Product Details
Supplier Bethyl Laboratories
Catalog #: A300-813A-T (View supplier product page)
Size 2 µg
Price $121.00
Antigen Brg1
Clone Polyclonal
Host Rabbit
Isotype IgG
Conjugate Unconjugated
Target Species Human, Mouse
Applications WB, IP, IHC
Description Rabbit anti-BRG1/SMARCA4 Antibody, Affinity Purified
About Brg1 and Purified
Brg1 The protein encoded by this gene is a member of the SWI/SNF family of proteins and is similar to the brahma protein of Drosophila. Members of this family have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein is part of the large ATP-dependent chromatin remodeling complex SNF/SWI, which is required for transcriptional activation of genes normally repressed by chromatin. In addition, this protein can bind BRCA1, as well as regulate the expression of the tumorigenic protein CD44. Mutations in this gene cause rhabdoid tumor predisposition syndrome type 2. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2012]
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Purified Excitation and Emission Spectra