CD27 / RealYellow 610 / M-T271

Product Details
Supplier BD Biosciences
Catalog #: 571274 (View supplier product page)
Size 100 Tests
Price $370.00
Antigen CD27
Clone M-T271
Host Mouse
Isotype IgG1 κ
Conjugate RealYellow 610
Target Species Baboon, Cynomolgus macaque, Human, Rhesus macaque
Applications FC
Description Hu CD27 RY610 M-T271 100Tst
About CD27 and RealYellow 610
CD27 The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is required for generation and long-term maintenance of T cell immunity. It binds to ligand CD70, and plays a key role in regulating B-cell activation and immunoglobulin synthesis. This receptor transduces signals that lead to the activation of NF-kappaB and MAPK8/JNK. Adaptor proteins TRAF2 and TRAF5 have been shown to mediate the signaling process of this receptor. CD27-binding protein (SIVA), a proapoptotic protein, can bind to this receptor and is thought to play an important role in the apoptosis induced by this receptor. [provided by RefSeq, Jul 2008]
RealYellow 610 RealYellow™610 from BD Biosciences is a spectral equivalent to BD Horizon™ PE-CF594 (BD Biosciences) and PE-Dazzle™ 594 (BioLegend) however with more discrete excitation by the 561nm laser and minimal cross-laser excitation off the 488-nm blue laser. This limited cross-beam excitation will translate to lower complexity index scores and lower spillover spreading error in high parameter spectral flow cytometry applications than PE tandem fluorophores.
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RealYellow 610 Excitation and Emission Spectra