CCR7 Monoclonal / NovaFluor Red 700 / 3D12

Product Details
Supplier Thermo Fisher Scientific
Catalog #: H085T03R03-A (View supplier product page)
Size 100 Tests
Price $395.00
Antigen CCR7
Clone 3D12
Host Rat
Isotype IgG2a κ
Conjugate NovaFluor Red 700
Target Species Human
Applications FC
Description CD197 (CCR7) Monoclonal Antibody (3D12), NovaFluor Red 700, eBioscience
About CCR7 and NovaFluor Red 700
CCR7 The protein encoded by this gene is a member of the G protein-coupled receptor family. This receptor was identified as a gene induced by the Epstein-Barr virus (EBV), and is thought to be a mediator of EBV effects on B lymphocytes. This receptor is expressed in various lymphoid tissues and activates B and T lymphocytes. It has been shown to control the migration of memory T cells to inflamed tissues, as well as stimulate dendritic cell maturation. The chemokine (C-C motif) ligand 19 (CCL19/ECL) has been reported to be a specific ligand of this receptor. Signals mediated by this receptor regulate T cell homeostasis in lymph nodes, and may also function in the activation and polarization of T cells, and in chronic inflammation pathogenesis. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Sep 2014]
NovaFluor Red 700 The NovaFluor family of fluorescent polymers from Thermo Fisher Scientific are a novel reagent for traditional and spectral flow cytometry. These fluorophores are comprised of a DNA backbone polymer integrated with fluorophore substituted nucleosides to create a potent donor molecule. Tandem fluophores with long Stokes' Shift enable brighter, spectrally discrete, tunable fluorescent polymers as an alternative to traditional simple organic structures, protein-based fluorophores as well as the Horizon Brilliantâ„¢ family of fluorescent polymers from BD. NovaFluor Red 700 has an excitation peak at 637 nm and an emission peak at 700 nm.
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NovaFluor Red 700 Excitation and Emission Spectra