PD-1 Monoclonal / Brilliant Ultraviolet 661 / eBioJ105 (J105)

Product Details
Supplier Thermo Fisher Scientific
Catalog #: 376-2799-42 (View supplier product page)
Size 100 Tests
Price $395.00
Antigen PD-1
Clone eBioJ105 (J105)
Host Mouse
Isotype IgG1 κ
Conjugate Brilliant Ultraviolet 661
Target Species Human, Rhesus macaque
Applications FC
Description CD279 (PD-1) Monoclonal Antibody (eBioJ105 (J105)), Brilliant Ultra Violet 661, eBioscience
About PD-1 and Brilliant Ultraviolet 661
PD-1 Programmed cell death protein 1 (PDCD1) is an immune-inhibitory receptor expressed in activated T cells; it is involved in the regulation of T-cell functions, including those of effector CD8+ T cells. In addition, this protein can also promote the differentiation of CD4+ T cells into T regulatory cells. PDCD1 is expressed in many types of tumors including melanomas, and has demonstrated to play a role in anti-tumor immunity. Moreover, this protein has been shown to be involved in safeguarding against autoimmunity, however, it can also contribute to the inhibition of effective anti-tumor and anti-microbial immunity. [provided by RefSeq, Aug 2020]
Brilliant Ultraviolet 661 Brilliant™ UltraViolet 661 (BUV661) is a red-emitting tandem fluorophore that combines BD Horizon® BUV395 and an acceptor dye. It can be excited by the 355 nm UV laser and collected using a 670/25 bandpass filter. BUV661 has an excitation peak at 498 nm and an emission peak at 657 nm This dye is part of the Brilliant™ UltraViolet dye family, developed and sold by BD Biosciences. This family of dyes uses BUV395 as the donor so that all dyes in the family can be excited by the 355 nm UV laser. Depending on the acceptor, the dyes in this family have different relative brightness ratings.
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Brilliant Ultraviolet 661 Excitation and Emission Spectra