CD27 / ABflo 488 / ARC67086-ABflo488

Product Details
Supplier ABclonal
Catalog #: A25450-500T (View supplier product page)
Size 500T
Price $248.00
Antigen CD27
Clone ARC67086-ABflo488
Host Rabbit
Isotype IgG
Conjugate ABflo 488
Target Species Mouse
Applications FC
About CD27 and ABflo 488
CD27 The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is required for generation and long-term maintenance of T cell immunity. It binds to ligand CD70, and plays a key role in regulating B-cell activation and immunoglobulin synthesis. This receptor transduces signals that lead to the activation of NF-kappaB and MAPK8/JNK. Adaptor proteins TRAF2 and TRAF5 have been shown to mediate the signaling process of this receptor. CD27-binding protein (SIVA), a proapoptotic protein, can bind to this receptor and is thought to play an important role in the apoptosis induced by this receptor. [provided by RefSeq, Jul 2008]
ABflo 488 ABflo 488® from ABclonal has an excitation peak at 491 nm and an emission peak at 516 nm and is similar in size, brightness and application to Alexa Fluor™ 488 (ThermoFisher Scientific), MaxLight™ 488 (US Biological), DyLight 488 and FITC. It is commonly used in flow cytometry and fluorescence microscopy applications.
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ABflo 488 Excitation and Emission Spectra