CD86 ABflo 488 (ARC54012-ABf488, Rabbit) - Reactivity: Human

Product Details
Conjugate ABflo 488
Clone ARC54012-ABf488
Target Species Human
Applications FC
Supplier ABclonal
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About CD86
This gene encodes a type I membrane protein that is a member of the immunoglobulin superfamily. This protein is expressed by antigen-presenting cells, and it is the ligand for two proteins at the cell surface of T cells, CD28 antigen and cytotoxic T-lymphocyte-associated protein 4. Binding of this protein with CD28 antigen is a costimulatory signal for activation of the T-cell. Binding of this protein with cytotoxic T-lymphocyte-associated protein 4 negatively regulates T-cell activation and diminishes the immune response. Alternative splicing results in several transcript variants encoding different isoforms.[provided by RefSeq, May 2011]
About ABflo 488
ABflo 488® from ABclonal has an excitation peak at 491 nm and an emission peak at 516 nm and is similar in size, brightness and application to Alexa Fluor™ 488 (ThermoFisher Scientific), MaxLight™ 488 (US Biological), DyLight 488 and FITC. It is commonly used in flow cytometry and fluorescence microscopy applications.
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$358.00