IL-21 R / Biotin / 4A9

Product Details
Supplier Leinco
Catalog #: I-1251-500μg (View supplier product page)
Size 500 μg
Price $256.75
Antigen IL-21 R
Clone 4A9
Host Rat
Isotype IgG2a κ
Conjugate Biotin
Target Species Mouse
Applications FC
About IL-21 R and Biotin
IL-21 R The protein encoded by this gene is a cytokine receptor for interleukin 21 (IL21). It belongs to the type I cytokine receptors, and has been shown to form a heterodimeric receptor complex with the common gamma-chain, a receptor subunit also shared by the receptors for interleukin 2, 4, 7, 9, and 15. This receptor transduces the growth promoting signal of IL21, and is important for the proliferation and differentiation of T cells, B cells, and natural killer (NK) cells. The ligand binding of this receptor leads to the activation of multiple downstream signaling molecules, including JAK1, JAK3, STAT1, and STAT3. Knockout studies of a similar gene in mouse suggest a role for this gene in regulating immunoglobulin production. Three alternatively spliced transcript variants have been described. [provided by RefSeq, Jul 2010]
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Biotin Excitation and Emission Spectra