CD8a / RayBright Red 780 / OKT8

Product Details
Supplier RayBiotech
Catalog #: 136-27025-100 (View supplier product page)
Size 100 Tests
Price $264.00
Antigen CD8a
Clone OKT8
Host Mouse
Isotype IgG2a κ
Conjugate RayBright Red 780
Target Species Human
Applications FC
Description RayBright® Red 780 Human CD8a Antibody [clone: OKT8], monoclonal Mouse IgG2a kappa. Validated for flow cytometry.
About CD8a and RayBright Red 780
CD8a The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen acts as a coreceptor with the T-cell receptor on the T lymphocyte to recognize antigens displayed by an antigen presenting cell in the context of class I MHC molecules. The coreceptor functions as either a homodimer composed of two alpha chains or as a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. This gene encodes the CD8 alpha chain. Multiple transcript variants encoding different isoforms have been found for this gene. The major protein isoforms of this gene differ by the presence or absence of a transmembrane domain and thus differ in being a membrane-anchored or secreted protein. [provided by RefSeq, May 2020]
RayBright Red 780 RayBright Red 780 is a red-emitting tandem fluorophore of APC, excited by the 633 nm red laser and transfers energy to deeper red-emitting acceptor molecule which emits light that can be captured with a 780/60 nm bandpass filter. APC-eF780 has an excitation peak at 645 nm and an emission peak at 767 nm, and is spectrally similar to APC-eFluor 780 (ThermoFisher), APC-Cy® 7 (GE Healthcare) APC-H7 (BD Biosciences), APC-Vio®770 (Miltenyi Biotec) and APC-Fire™ 750 (BioLegend).
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RayBright Red 780 Excitation and Emission Spectra