CCR9 / RayBright Red 647 / LS129-3C3-E3-1 [3C3]

Product Details
Supplier RayBiotech
Catalog #: 136-24082-025 (View supplier product page)
Size 25 Tests
Price $125.00
Antigen CCR9
Clone LS129-3C3-E3-1 [3C3]
Host Mouse
Isotype IgG2b
Conjugate RayBright Red 647
Target Species Human
Applications FC
Description Human CD199 Antibody [clone: LS129-3C3-E3-1 [3C3]], monoclonal mouse IgG2b. Validated for flow cytometry.
About CCR9 and RayBright Red 647
CCR9 The protein encoded by this gene is a G protein-coupled receptor with seven transmembrane domains that belongs to the beta chemokine receptor family. Chemokines and their receptors are key regulators of thymocyte migration and maturation in normal and inflammation conditions. This gene is differentially expressed in T lymphocytes of the small intestine and colon, and its interaction with chemokine 25 contributes to intestinal intra-epithelial lymphocyte homing to the small intestine. This suggests a role for this gene in directing immune responses to different segments of the gastrointestinal tract. This gene and its exclusive ligand, chemokine 25, are overexpressed in a variety of malignant tumors and are closely associated with tumor proliferation, apoptosis, invasion, migration and drug resistance. This gene maps to the chemokine receptor gene cluster. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2020]
RayBright Red 647 RayBright Red 647 from RayBiotech has an excitation peak at 646 nm and an emission peak at 660 nm. It is similar in structure, size and application to Alexa Fluor 647 (ThermoFisher) and CF647 (Biotium). It is useful in fluorescence microscopy and flow cytometry applications.
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RayBright Red 647 Excitation and Emission Spectra