TNF RayBright Red 647 (Mouse) - Reactivity: Human
Product Details
| Description | Human TNF-alpha Antibody, monoclonal mouse IgG2b. Validated for flow cytometry. | |
|---|---|---|
| Conjugate | RayBright Red 647 | |
| Clone | ||
| Target Species | Human | |
| Applications | FC, IHC, ELISA | |
| Supplier | RayBiotech | |
| Catalog # | Sign in to view product details, citations, and spectra | |
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About TNF
This gene encodes a multifunctional proinflammatory cytokine that belongs to the tumor necrosis factor (TNF) superfamily. This cytokine is mainly secreted by macrophages. It can bind to, and thus functions through its receptors TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. This cytokine is involved in the regulation of a wide spectrum of biological processes including cell proliferation, differentiation, apoptosis, lipid metabolism, and coagulation. This cytokine has been implicated in a variety of diseases, including autoimmune diseases, insulin resistance, psoriasis, rheumatoid arthritis ankylosing spondylitis, tuberculosis, autosomal dominant polycystic kidney disease, and cancer. Mutations in this gene affect susceptibility to cerebral malaria, septic shock, and Alzheimer disease. Knockout studies in mice also suggested the neuroprotective function of this cytokine. [provided by RefSeq, Aug 2020]
This gene encodes a multifunctional proinflammatory cytokine that belongs to the tumor necrosis factor (TNF) superfamily. This cytokine is mainly secreted by macrophages. It can bind to, and thus functions through its receptors TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. This cytokine is involved in the regulation of a wide spectrum of biological processes including cell proliferation, differentiation, apoptosis, lipid metabolism, and coagulation. This cytokine has been implicated in a variety of diseases, including autoimmune diseases, insulin resistance, psoriasis, rheumatoid arthritis ankylosing spondylitis, tuberculosis, autosomal dominant polycystic kidney disease, and cancer. Mutations in this gene affect susceptibility to cerebral malaria, septic shock, and Alzheimer disease. Knockout studies in mice also suggested the neuroprotective function of this cytokine. [provided by RefSeq, Aug 2020]
About RayBright Red 647
RayBright Red 647 from RayBiotech has an excitation peak at 646 nm and an emission peak at 660 nm. It is similar in structure, size and application to Alexa Fluor 647 (ThermoFisher) and CF647 (Biotium). It is useful in fluorescence microscopy and flow cytometry applications.
RayBright Red 647 from RayBiotech has an excitation peak at 646 nm and an emission peak at 660 nm. It is similar in structure, size and application to Alexa Fluor 647 (ThermoFisher) and CF647 (Biotium). It is useful in fluorescence microscopy and flow cytometry applications.
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Validation References
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