CD11b / RayBright APC / M1/70.15.11.5.HL

Product Details
Supplier RayBiotech
Catalog #: 135-25001-025 (View supplier product page)
Size 25 Tests
Price $55.00
Antigen CD11b
Clone M1/70.15.11.5.HL
Host Rat
Isotype IgG2b κ
Conjugate RayBright APC
Target Species Human, Mouse
Applications FC, IHC, Mass Cytometry, IP, Block, IF
Description Human / Mouse CD11b Antibody [clone: M1/70.15.11.5.HL], monoclonal rat IgG2b kappa. Validated for flow cytometry.
About CD11b and RayBright APC
CD11b This gene encodes the integrin alpha M chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as macrophage receptor 1 ('Mac-1'), or inactivated-C3b (iC3b) receptor 3 ('CR3'). The alpha M beta 2 integrin is important in the adherence of neutrophils and monocytes to stimulated endothelium, and also in the phagocytosis of complement coated particles. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009]
RayBright APC Allophycocyanin (APC) is a fluorescent protein derived from cyanobacteria and red algae and a potent donor fluorophore to create tandem dyes that can be excited off the 633-650 nm laser. APC has an excitation peak at 650 nm and a emission peak at 660 nm.
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RayBright APC Excitation and Emission Spectra