CD11b Monoclonal / NovaFluor Blue 610 / 70S / ICRF44

Product Details
Supplier Thermo Fisher Scientific
Catalog #: H036T02B06-A (View supplier product page)
Size 25 Tests
Price $178.00
Antigen CD11b
Clone ICRF44
Host Mouse
Isotype IgG1 κ
Conjugate NovaFluor Blue 610 / 70S
Target Species Baboon, Chimpanzee, Cynomolgus macaque, Human, Rhesus macaque
Applications FC
Description CD11b Monoclonal Antibody (ICRF44), NovaFluor Blue 610-70S, eBioscience
About CD11b and NovaFluor Blue 610 / 70S
CD11b This gene encodes the integrin alpha M chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as macrophage receptor 1 ('Mac-1'), or inactivated-C3b (iC3b) receptor 3 ('CR3'). The alpha M beta 2 integrin is important in the adherence of neutrophils and monocytes to stimulated endothelium, and also in the phagocytosis of complement coated particles. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009]
NovaFluor Blue 610 / 70S The NovaFluor family of fluorescent polymers from Thermo Fisher Scientific are a novel reagent for traditional and spectral flow cytometry. These fluorophores are comprised of a DNA backbone polymer integrated with fluorophore substituted nucleosides to create a potent donor molecule. Tandem fluophores with long Stokes' Shift enable brighter, spectrally discrete, tunable fluorescent polymers as an alternative to traditional simple organic structures, protein-based fluorophores as well as the Horizon Brilliantâ„¢ family of fluorescent polymers from BD. NovaFluor Blue 610/70S is designed to be discreetly excited by the 488 nm laser and has an excitation peak at 496 nm and an emission peak at 614 nm. NovaFluor Blue 610/ 70S is bigger and brighter than NovaFluor Blue 610/ 30S.
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NovaFluor Blue 610 / 70S Excitation and Emission Spectra