IL-18 / Biotin / ABT-325 (A-794722.0; 2.5(E))
IL-18 / Biotin / ABT-325 (A-794722.0; 2.5(E))
Product Details
| Supplier | Absolute Antibody | |
|---|---|---|
| Catalog #: | Ab03375-23.0-biotin (View supplier product page) | |
| Size | 200 μg | |
| Price | ||
| Antigen | IL-18 | |
| Clone | ABT-325 (A-794722.0; 2.5(E)) | |
| Host | Rabbit | |
| Isotype | IgG | |
| Conjugate | Biotin | |
| Target Species | Cynomolgus macaque, Human | |
| Applications | IP, ELISA, FC, Block/Neutralize | |
| Description | Anti-IL-18 [ABT-325 (A-794722.0; 2.5(E))] |
About IL-18 and Biotin
| IL-18 | The protein encoded by this gene is a proinflammatory cytokine of the IL-1 family that is constitutively found as a precursor within the cytoplasm of a variety of cells including macrophages and keratinocytes. The inactive IL-18 precursor is processed to its active form by caspase-1, and is capable of stimulating interferon gamma production, and of regulating both T helper (Th) 1 and Th2 responses. This cytokine has been implicated in the injury of different organs, and in potentially fatal conditions characterized by a cytokine storm. In humans, IL-18 gene is located on chromosome 11. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Aug 2020] |
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Citations
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