CD357 / Biotin / DTA-1
CD357 / Biotin / DTA-1
Product Details
| Supplier | Absolute Antibody | |
|---|---|---|
| Catalog #: | Ab01060-2.3-biotin (View supplier product page) | |
| Size | 200 μg | |
| Price | ||
| Antigen | CD357 | |
| Clone | DTA-1 | |
| Host | Mouse | |
| Isotype | IgG2a | |
| Conjugate | Biotin | |
| Target Species | Mouse | |
| Applications | FC, WB, IP, Agonist Activity | |
| Description | Anti-GITR [DTA-1] |
About CD357 and Biotin
| CD357 | This gene encodes a member of the TNF-receptor superfamily. The encoded receptor has been shown to have increased expression upon T-cell activation, and it is thought to play a key role in dominant immunological self-tolerance maintained by CD25(+)CD4(+) regulatory T cells. Knockout studies in mice also suggest the role of this receptor is in the regulation of CD3-driven T-cell activation and programmed cell death. Three alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq, Feb 2011] |
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Citations
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