CD148 / Biotin / 33A1_81
CD148 / Biotin / 33A1_81
Product Details
| Supplier | Absolute Antibody | |
|---|---|---|
| Catalog #: | Ab02191-23.0-biotin (View supplier product page) | |
| Size | 200 μg | |
| Price | ||
| Antigen | CD148 | |
| Clone | 33A1_81 | |
| Host | Rabbit | |
| Isotype | IgG | |
| Conjugate | Biotin | |
| Target Species | Human | |
| Applications | ELISA, IF, Surface Plasmon Resonance | |
| Description | Anti-CD148 [33A1_81] |
About CD148 and Biotin
| CD148 | The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes, including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region containing five fibronectin type III repeats, a single transmembrane region, and a single intracytoplasmic catalytic domain, and thus represents a receptor-type PTP. This protein is present in all hematopoietic lineages, and was shown to negatively regulate T cell receptor signaling possibly through interfering with the phosphorylation of Phospholipase C Gamma 1 and Linker for Activation of T Cells. This protein can also dephosphorylate the PDGF beta receptor, and may be involved in UV-induced signal transduction. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] |
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Citations
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