CCR7 / Biotin / mAb 22
CCR7 / Biotin / mAb 22
Product Details
| Supplier | Absolute Antibody | |
|---|---|---|
| Catalog #: | Ab04231-10.0-biotin (View supplier product page) | |
| Size | 100 μg | |
| Price | ||
| Antigen | CCR7 | |
| Clone | mAb 22 | |
| Host | Human | |
| Isotype | IgG1 | |
| Conjugate | Biotin | |
| Target Species | Human | |
| Applications | ELISA, Block/Neutralize | |
| Description | Anti-CCR7 [mAb 22] |
About CCR7 and Biotin
| CCR7 | The protein encoded by this gene is a member of the G protein-coupled receptor family. This receptor was identified as a gene induced by the Epstein-Barr virus (EBV), and is thought to be a mediator of EBV effects on B lymphocytes. This receptor is expressed in various lymphoid tissues and activates B and T lymphocytes. It has been shown to control the migration of memory T cells to inflamed tissues, as well as stimulate dendritic cell maturation. The chemokine (C-C motif) ligand 19 (CCL19/ECL) has been reported to be a specific ligand of this receptor. Signals mediated by this receptor regulate T cell homeostasis in lymph nodes, and may also function in the activation and polarization of T cells, and in chronic inflammation pathogenesis. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Sep 2014] |
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Citations
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