CD207 / HRP / 4C7
CD207 / HRP / 4C7
Product Details
| Supplier | Absolute Antibody | |
|---|---|---|
| Catalog #: | Ab00643-2.0-hrp (View supplier product page) | |
| Size | 200 μg | |
| Price | ||
| Antigen | CD207 | |
| Clone | 4C7 | |
| Host | Mouse | |
| Isotype | IgG2a | |
| Conjugate | HRP | |
| Target Species | Cynomolgus macaque, Human, Mouse, Porcine | |
| Applications | FC, IHC-Fr | |
| Description | Anti-Langerin [4C7] |
About CD207 and HRP
| CD207 | The protein encoded by this gene is expressed only in Langerhans cells which are immature dendritic cells of the epidermis and mucosa. It is localized in the Birbeck granules, organelles present in the cytoplasm of Langerhans cells and consisting of superimposed and zippered membranes. It is a C-type lectin with mannose binding specificity, and it has been proposed that mannose binding by this protein leads to internalization of antigen into Birbeck granules and providing access to a nonclassical antigen-processing pathway. Mutations in this gene result in Birbeck granules deficiency or loss of sugar binding activity. [provided by RefSeq, Aug 2010] |
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Citations
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