CD357 / FluoroProbes647h / YGITR765
CD357 / FluoroProbes647h / YGITR765
Product Details
Supplier | Absolute Antibody | |
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Catalog #: | Ab00631-8.4-fluoroprobes647h (View supplier product page) | |
Size | 200 μg | |
Price | ||
Antigen | CD357 | |
Clone | YGITR765 | |
Host | Rat | |
Isotype | IgG2b | |
Conjugate | FluoroProbes647h | |
Target Species | Mouse | |
Applications | FC, Block/Neutralize | |
Description | Anti-GITR [YGITR765] |
About CD357 and FluoroProbes647h
CD357 | This gene encodes a member of the TNF-receptor superfamily. The encoded receptor has been shown to have increased expression upon T-cell activation, and it is thought to play a key role in dominant immunological self-tolerance maintained by CD25(+)CD4(+) regulatory T cells. Knockout studies in mice also suggest the role of this receptor is in the regulation of CD3-driven T-cell activation and programmed cell death. Three alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq, Feb 2011] | |
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FluoroProbes647h | FluoProbes 647H from Abcam has an excitation peak at 650 nm and an emission peak at 672 nm. It can be used in flow cytometry and fluorescence microscopy. |