CD11b / FluoroProbes647h / M1/70
CD11b / FluoroProbes647h / M1/70
Product Details
| Supplier | Absolute Antibody | |
|---|---|---|
| Catalog #: | Ab01114-2.0-fluoroprobes647h (View supplier product page) | |
| Size | 200 μg | |
| Price | ||
| Antigen | CD11b | |
| Clone | M1/70 | |
| Host | Mouse | |
| Isotype | IgG2a | |
| Conjugate | FluoroProbes647h | |
| Target Species | Mouse | |
| Applications | FC, WB, ELISA, IF, IHC, ICC, IP, Block/Neutralize, Functional | |
| Description | Anti-CD11b [M1/70] |
About CD11b and FluoroProbes647h
| CD11b | This gene encodes the integrin alpha M chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as macrophage receptor 1 ('Mac-1'), or inactivated-C3b (iC3b) receptor 3 ('CR3'). The alpha M beta 2 integrin is important in the adherence of neutrophils and monocytes to stimulated endothelium, and also in the phagocytosis of complement coated particles. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009] | |
|---|---|---|
| FluoroProbes647h | FluoProbes 647H from Abcam has an excitation peak at 650 nm and an emission peak at 672 nm. It can be used in flow cytometry and fluorescence microscopy. |
Citations
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