CD11a / FluoroProbes647h / hu1124 (Efalizumab)
CD11a / FluoroProbes647h / hu1124 (Efalizumab)
Product Details
| Supplier | Absolute Antibody | |
|---|---|---|
| Catalog #: | Ab00535-10.0-fluoroprobes647h (View supplier product page) | |
| Size | 200 μg | |
| Price | ||
| Antigen | CD11a | |
| Clone | hu1124 (Efalizumab) | |
| Host | Human | |
| Isotype | IgG1 | |
| Conjugate | FluoroProbes647h | |
| Target Species | Human | |
| Applications | Block, FC | |
| Description | Anti-CD11a [hu1124 (Efalizumab)] |
About CD11a and FluoroProbes647h
| CD11a | ITGAL encodes the integrin alpha L chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form the integrin lymphocyte function-associated antigen-1 (LFA-1), which is expressed on all leukocytes. LFA-1 plays a central role in leukocyte intercellular adhesion through interactions with its ligands, ICAMs 1-3 (intercellular adhesion molecules 1 through 3), and also functions in lymphocyte costimulatory signaling. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] | |
|---|---|---|
| FluoroProbes647h | FluoProbes 647H from Abcam has an excitation peak at 650 nm and an emission peak at 672 nm. It can be used in flow cytometry and fluorescence microscopy. |
Citations
| Additional Sources |
|
|---|
