VEGFR2 / Fluorescein / IMC-1121B (Ramucirumab)
VEGFR2 / Fluorescein / IMC-1121B (Ramucirumab)
Product Details
| Supplier | Absolute Antibody | |
|---|---|---|
| Catalog #: | Ab03058-3.0-fluorescein (View supplier product page) | |
| Size | 200 μg | |
| Price | ||
| Antigen | VEGFR2 | |
| Clone | IMC-1121B (Ramucirumab) | |
| Host | Mouse | |
| Isotype | IgG2b | |
| Conjugate | Fluorescein | |
| Target Species | Human | |
| Applications | FC, IHC, X-Ray Crystallography, In Vitro, In Vivo | |
| Description | Anti-VEGFR2 [IMC-1121B (Ramucirumab)] |
About VEGFR2 and Fluorescein
| VEGFR2 | Vascular endothelial growth factor (VEGF) is a major growth factor for endothelial cells. This gene encodes one of the two receptors of the VEGF. This receptor, known as kinase insert domain receptor, is a type III receptor tyrosine kinase. It functions as the main mediator of VEGF-induced endothelial proliferation, survival, migration, tubular morphogenesis and sprouting. The signalling and trafficking of this receptor are regulated by multiple factors, including Rab GTPase, P2Y purine nucleotide receptor, integrin alphaVbeta3, T-cell protein tyrosine phosphatase, etc.. Mutations of this gene are implicated in infantile capillary hemangiomas. [provided by RefSeq, May 2009] | |
|---|---|---|
| Fluorescein | Fluorescein is an organic fluorophore first synthesized by Aldolf Bayer in 1871. FITC, an amine-reactive derivative, is also a commonly used name for this dye. It has an excitation peak at 494 nm and an emission peak at 512 nm. |
Citations
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