PD-1 / Fluorescein / 5C4.B8 (Nivolumab)
PD-1 / Fluorescein / 5C4.B8 (Nivolumab)
Product Details
| Supplier | Absolute Antibody | |
|---|---|---|
| Catalog #: | Ab00791-10.0-fluorescein (View supplier product page) | |
| Size | 100 μg | |
| Price | ||
| Antigen | PD-1 | |
| Clone | 5C4.B8 (Nivolumab) | |
| Host | Human | |
| Isotype | IgG1 | |
| Conjugate | Fluorescein | |
| Target Species | Cynomolgus macaque, Human | |
| Applications | IHC, FC, Surface Plasmon Resonance, Block/Neutralize | |
| Description | Anti-PD-1 [5C4.B8 (Nivolumab)] |
About PD-1 and Fluorescein
| PD-1 | Programmed cell death protein 1 (PDCD1) is an immune-inhibitory receptor expressed in activated T cells; it is involved in the regulation of T-cell functions, including those of effector CD8+ T cells. In addition, this protein can also promote the differentiation of CD4+ T cells into T regulatory cells. PDCD1 is expressed in many types of tumors including melanomas, and has demonstrated to play a role in anti-tumor immunity. Moreover, this protein has been shown to be involved in safeguarding against autoimmunity, however, it can also contribute to the inhibition of effective anti-tumor and anti-microbial immunity. [provided by RefSeq, Aug 2020] | |
|---|---|---|
| Fluorescein | Fluorescein is an organic fluorophore first synthesized by Aldolf Bayer in 1871. FITC, an amine-reactive derivative, is also a commonly used name for this dye. It has an excitation peak at 494 nm and an emission peak at 512 nm. |
Citations
| Additional Sources |
|
|---|
