FluoroFinder

	Supplier	Absolute Antibody
	Catalog #:	Ab03148-2.0-fluorescein (View supplier product page)
	Size	200 μg
	Price
	Antigen	p53
	Clone	70237-85
	Host	Mouse
	Isotype	IgG2a
	Conjugate	Fluorescein
	Target Species	Human
	Applications	ELISA, WB, IHC
	Description	Anti-p53 [70237-85]

	p53	This gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li-Fraumeni syndrome. Alternative splicing of this gene and the use of alternate promoters result in multiple transcript variants and isoforms. Additional isoforms have also been shown to result from the use of alternate translation initiation codons from identical transcript variants (PMIDs: 12032546, 20937277). [provided by RefSeq, Dec 2016]
	Fluorescein	Fluorescein is an organic fluorophore first synthesized by Aldolf Bayer in 1871. FITC, an amine-reactive derivative, is also a commonly used name for this dye. It has an excitation peak at 494 nm and an emission peak at 512 nm.

	Additional Sources

p53 / Fluorescein / 70237-85