Integrin beta 7 / Fluorescein / FIB27

Product Details
Supplier Absolute Antibody
Catalog #: Ab00627-23.0-fluorescein (View supplier product page)
Size 200 μg
Price
Antigen Integrin beta 7
Clone FIB27
Host Rabbit
Isotype IgG
Conjugate Fluorescein
Target Species Human, Mouse
Applications FC, IP, Block/Neutralize
Description Anti-Integrin beta-7 [FIB27]
About Integrin beta 7 and Fluorescein
Integrin beta 7 This gene encodes a protein that is a member of the integrin superfamily. Members of this family are adhesion receptors that function in signaling from the extracellular matrix to the cell. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. The encoded protein forms dimers with an alpha4 chain or an alphaE chain and plays a role in leukocyte adhesion. Dimerization with alpha4 forms a homing receptor for migration of lymphocytes to the intestinal mucosa and Peyer's patches. Dimerization with alphaE permits binding to the ligand epithelial cadherin, a calcium-dependent adhesion molecule. Alternate splicing results in multiple transcript variants. Additional alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known. [provided by RefSeq, Sep 2013]
Fluorescein Fluorescein is an organic fluorophore first synthesized by Aldolf Bayer in 1871. FITC, an amine-reactive derivative, is also a commonly used name for this dye. It has an excitation peak at 494 nm and an emission peak at 512 nm.
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Fluorescein Excitation and Emission Spectra