Glypican 3 / Fluorescein / 4C11
Glypican 3 / Fluorescein / 4C11
Product Details
| Supplier | Absolute Antibody | |
|---|---|---|
| Catalog #: | Ab03199-23.0-fluorescein (View supplier product page) | |
| Size | 200 μg | |
| Price | ||
| Antigen | Glypican 3 | |
| Clone | 4C11 | |
| Host | Rabbit | |
| Isotype | IgG | |
| Conjugate | Fluorescein | |
| Target Species | Human | |
| Applications | ELISA, WB, IHC | |
| Description | Anti-Glypican 3 [4C11] |
About Glypican 3 and Fluorescein
| Glypican 3 | Cell surface heparan sulfate proteoglycans are composed of a membrane-associated protein core substituted with a variable number of heparan sulfate chains. Members of the glypican-related integral membrane proteoglycan family (GRIPS) contain a core protein anchored to the cytoplasmic membrane via a glycosyl phosphatidylinositol linkage. These proteins may play a role in the control of cell division and growth regulation. The protein encoded by this gene can bind to and inhibit the dipeptidyl peptidase activity of CD26, and it can induce apoptosis in certain cell types. Deletion mutations in this gene are associated with Simpson-Golabi-Behmel syndrome, also known as Simpson dysmorphia syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2009] | |
|---|---|---|
| Fluorescein | Fluorescein is an organic fluorophore first synthesized by Aldolf Bayer in 1871. FITC, an amine-reactive derivative, is also a commonly used name for this dye. It has an excitation peak at 494 nm and an emission peak at 512 nm. |
Citations
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