FluoroFinder

	Supplier	Absolute Antibody
	Catalog #:	Ab01766-1.29-fluorescein (View supplier product page)
	Size	100 μg
	Price
	Antigen	CBP
	Clone	RAB-C530
	Host	Mouse
	Isotype	Fab Fragment
	Conjugate	Fluorescein
	Target Species	Human
	Applications	FC, IP, IF
	Description	Anti-CREBBP [RAB-C530]

	CBP	This gene is ubiquitously expressed and is involved in the transcriptional coactivation of many different transcription factors. First isolated as a nuclear protein that binds to cAMP-response element binding protein (CREB), this gene is now known to play critical roles in embryonic development, growth control, and homeostasis by coupling chromatin remodeling to transcription factor recognition. The protein encoded by this gene has intrinsic histone acetyltransferase activity and also acts as a scaffold to stabilize additional protein interactions with the transcription complex. This protein acetylates both histone and non-histone proteins. This protein shares regions of very high sequence similarity with protein p300 in its bromodomain, cysteine-histidine-rich regions, and histone acetyltransferase domain. Mutations in this gene cause Rubinstein-Taybi syndrome (RTS). Chromosomal translocations involving this gene have been associated with acute myeloid leukemia. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Feb 2009]
	Fluorescein	Fluorescein is an organic fluorophore first synthesized by Aldolf Bayer in 1871. FITC, an amine-reactive derivative, is also a commonly used name for this dye. It has an excitation peak at 494 nm and an emission peak at 512 nm.

	Additional Sources

CBP / Fluorescein / RAB-C530