CD86 / Fluorescein / PO3
CD86 / Fluorescein / PO3
Product Details
| Supplier | Absolute Antibody | |
|---|---|---|
| Catalog #: | Ab01029-2.0-fluorescein (View supplier product page) | |
| Size | 200 μg | |
| Price | ||
| Antigen | CD86 | |
| Clone | PO3 | |
| Host | Mouse | |
| Isotype | IgG2a | |
| Conjugate | Fluorescein | |
| Target Species | Mouse | |
| Applications | FC, WB, IHC, Block/Neutralize, Functional | |
| Description | Anti-CD86 [PO3] |
About CD86 and Fluorescein
| CD86 | This gene encodes a type I membrane protein that is a member of the immunoglobulin superfamily. This protein is expressed by antigen-presenting cells, and it is the ligand for two proteins at the cell surface of T cells, CD28 antigen and cytotoxic T-lymphocyte-associated protein 4. Binding of this protein with CD28 antigen is a costimulatory signal for activation of the T-cell. Binding of this protein with cytotoxic T-lymphocyte-associated protein 4 negatively regulates T-cell activation and diminishes the immune response. Alternative splicing results in several transcript variants encoding different isoforms.[provided by RefSeq, May 2011] | |
|---|---|---|
| Fluorescein | Fluorescein is an organic fluorophore first synthesized by Aldolf Bayer in 1871. FITC, an amine-reactive derivative, is also a commonly used name for this dye. It has an excitation peak at 494 nm and an emission peak at 512 nm. |
Citations
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