CD86 / Fluorescein / OX-48
CD86 / Fluorescein / OX-48
Product Details
Supplier | Absolute Antibody | |
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Catalog #: | Ab00569-8.1-fluorescein (View supplier product page) | |
Size | 200 μg | |
Price | ||
Antigen | CD86 | |
Clone | OX-48 | |
Host | Rat | |
Isotype | IgG2b | |
Conjugate | Fluorescein | |
Target Species | Rat | |
Applications | FC, IF | |
Description | Anti-CD86 [OX-48] |
About CD86 and Fluorescein
CD86 | This gene encodes a type I membrane protein that is a member of the immunoglobulin superfamily. This protein is expressed by antigen-presenting cells, and it is the ligand for two proteins at the cell surface of T cells, CD28 antigen and cytotoxic T-lymphocyte-associated protein 4. Binding of this protein with CD28 antigen is a costimulatory signal for activation of the T-cell. Binding of this protein with cytotoxic T-lymphocyte-associated protein 4 negatively regulates T-cell activation and diminishes the immune response. Alternative splicing results in several transcript variants encoding different isoforms.[provided by RefSeq, May 2011] | |
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Fluorescein | Fluorescein is an organic fluorophore first synthesized by Aldolf Bayer in 1871. FITC, an amine-reactive derivative, is also a commonly used name for this dye. It has an excitation peak at 494 nm and an emission peak at 512 nm. |