FluoroFinder

	Supplier	Absolute Antibody
	Catalog #:	Ab00533-2.3-fluorescein (View supplier product page)
	Size	200 μg
	Price
	Antigen	CD8b
	Clone	YTS 156.7.7
	Host	Mouse
	Isotype	IgG2a
	Conjugate	Fluorescein
	Target Species	Mouse
	Applications	FC, IHC
	Description	Anti-CD8 beta [YTS 156.7.7]

	CD8b	The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen, acting as a coreceptor, and the T-cell receptor on the T lymphocyte recognize antigens displayed by an antigen presenting cell (APC) in the context of class I MHC molecules. The functional coreceptor is either a homodimer composed of two alpha chains, or a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. This gene encodes the CD8 beta chain isoforms. Multiple alternatively spliced transcript variants encoding distinct membrane associated or secreted isoforms have been described. A pseudogene, also located on chromosome 2, has been identified. [provided by RefSeq, May 2010]
	Fluorescein	Fluorescein is an organic fluorophore first synthesized by Aldolf Bayer in 1871. FITC, an amine-reactive derivative, is also a commonly used name for this dye. It has an excitation peak at 494 nm and an emission peak at 512 nm.

	Additional Sources

CD8b / Fluorescein / YTS 156.7.7