CD68 / Fluorescein / FA-11
CD68 / Fluorescein / FA-11
Product Details
| Supplier | Absolute Antibody | |
|---|---|---|
| Catalog #: | Ab01113-7.1-fluorescein (View supplier product page) | |
| Size | 200 μg | |
| Price | ||
| Antigen | CD68 | |
| Clone | FA-11 | |
| Host | Rat | |
| Isotype | IgG2a | |
| Conjugate | Fluorescein | |
| Target Species | Mouse | |
| Applications | FC, IHC, IP | |
| Description | Anti-CD68 [FA-11] |
About CD68 and Fluorescein
| CD68 | This gene encodes a 110-kD transmembrane glycoprotein that is highly expressed by human monocytes and tissue macrophages. It is a member of the lysosomal/endosomal-associated membrane glycoprotein (LAMP) family. The protein primarily localizes to lysosomes and endosomes with a smaller fraction circulating to the cell surface. It is a type I integral membrane protein with a heavily glycosylated extracellular domain and binds to tissue- and organ-specific lectins or selectins. The protein is also a member of the scavenger receptor family. Scavenger receptors typically function to clear cellular debris, promote phagocytosis, and mediate the recruitment and activation of macrophages. Alternative splicing results in multiple transcripts encoding different isoforms. [provided by RefSeq, Jul 2008] | |
|---|---|---|
| Fluorescein | Fluorescein is an organic fluorophore first synthesized by Aldolf Bayer in 1871. FITC, an amine-reactive derivative, is also a commonly used name for this dye. It has an excitation peak at 494 nm and an emission peak at 512 nm. |
Citations
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