CD134 / Fluorescein / OX86
CD134 / Fluorescein / OX86
Product Details
Supplier | Absolute Antibody | |
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Catalog #: | Ab00110-1.1-fluorescein (View supplier product page) | |
Size | 200 μg | |
Price | ||
Antigen | CD134 | |
Clone | OX86 | |
Host | Mouse | |
Isotype | IgG1 | |
Conjugate | Fluorescein | |
Target Species | Mouse | |
Applications | FC, Agonist Activity, IF, ELISA | |
Description | Anti-CD134 [OX86] |
About CD134 and Fluorescein
CD134 | The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor has been shown to activate NF-kappaB through its interaction with adaptor proteins TRAF2 and TRAF5. Knockout studies in mice suggested that this receptor promotes the expression of apoptosis inhibitors BCL2 and BCL2lL1/BCL2-XL, and thus suppresses apoptosis. The knockout studies also suggested the roles of this receptor in CD4+ T cell response, as well as in T cell-dependent B cell proliferation and differentiation. [provided by RefSeq, Jul 2008] | |
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Fluorescein | Fluorescein is an organic fluorophore first synthesized by Aldolf Bayer in 1871. FITC, an amine-reactive derivative, is also a commonly used name for this dye. It has an excitation peak at 494 nm and an emission peak at 512 nm. |