CD276 / Fluorescein / MJ18
CD276 / Fluorescein / MJ18
Product Details
| Supplier | Absolute Antibody | |
|---|---|---|
| Catalog #: | Ab00884-2.3-fluorescein (View supplier product page) | |
| Size | 200 μg | |
| Price | ||
| Antigen | CD276 | |
| Clone | MJ18 | |
| Host | Mouse | |
| Isotype | IgG2a | |
| Conjugate | Fluorescein | |
| Target Species | Mouse | |
| Applications | FC, Block | |
| Description | Anti-B7-H3 [MJ18] |
About CD276 and Fluorescein
| CD276 | The protein encoded by this gene belongs to the immunoglobulin superfamily, and thought to participate in the regulation of T-cell-mediated immune response. Studies show that while the transcript of this gene is ubiquitously expressed in normal tissues and solid tumors, the protein is preferentially expressed only in tumor tissues. Additionally, it was observed that the 3' UTR of this transcript contains a target site for miR29 microRNA, and there is an inverse correlation between the expression of this protein and miR29 levels, suggesting regulation of expression of this gene product by miR29. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011] | |
|---|---|---|
| Fluorescein | Fluorescein is an organic fluorophore first synthesized by Aldolf Bayer in 1871. FITC, an amine-reactive derivative, is also a commonly used name for this dye. It has an excitation peak at 494 nm and an emission peak at 512 nm. |
Citations
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