Urokinase / Unconjugated / mAb-112
Urokinase / Unconjugated / mAb-112
Product Details
| Supplier | Absolute Antibody | |
|---|---|---|
| Catalog #: | Ab00367-10.7-unconjugated (View supplier product page) | |
| Size | 200 μg | |
| Price | ||
| Antigen | Urokinase | |
| Clone | mAb-112 | |
| Host | Human | |
| Isotype | F(ab')2 | |
| Conjugate | Unconjugated | |
| Target Species | Human | |
| Applications | WB, Block/Neutralize | |
| Description | Anti-Urokinase-type plasminogen activator [mAb-112] |
About Urokinase and Purified
| Urokinase | This gene encodes a secreted serine protease that converts plasminogen to plasmin. The encoded preproprotein is proteolytically processed to generate A and B polypeptide chains. These chains associate via a single disulfide bond to form the catalytically inactive high molecular weight urokinase-type plasminogen activator (HMW-uPA). HMW-uPA can be further processed into the catalytically active low molecular weight urokinase-type plasminogen activator (LMW-uPA). This low molecular weight form does not bind to the urokinase-type plasminogen activator receptor. Mutations in this gene may be associated with Quebec platelet disorder and late-onset Alzheimer's disease. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed. [provided by RefSeq, Jan 2016] |
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Citations
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