CD49d / PE-Dazzle 594 / 9F10
CD49d / PE-Dazzle 594 / 9F10
Citations:
(2)
Product Details
| Supplier | BioLegend | |
|---|---|---|
| Catalog #: | 304325 (View supplier product page) | |
| Size | 25T | |
| Price | $147.00 | |
| Antigen | CD49d | |
| Clone | 9F10 | |
| Host | Mouse | |
| Isotype | IgG1 κ | |
| Conjugate | PE-Dazzle 594 | |
| Target Species | Cynomolgus macaque, Human, Rhesus macaque | |
| Applications | FC | |
| Description | PE/Dazzle 594 anti-human CD49d |
About CD49d and PE-Dazzle 594
| CD49d | The gene encodes a member of the integrin alpha chain family of proteins. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha 4 subunit. This subunit associates with a beta 1 or beta 7 subunit to form an integrin that may play a role in cell motility and migration. This integrin is a therapeutic target for the treatment of multiple sclerosis, Crohn's disease and inflammatory bowel disease. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2015] | |
|---|---|---|
| PE-Dazzle 594 | PE-Dazzle® 594 (RPE-Dazzle 594) from Biolegend is a red-emitting tandem fluorophore that combines pycoerythrin (PE) and Dazzle 594. The donor molecule, PE can be excited by the 488-nm blue, 532-nm green, or 561-nm yellow-green laser and and transfers energy to the acceptor molecule, Dazzle 594, which emitts light that can be captured with a 610/20 nm bandpass filter. PE-Dazzle 594 has an excitation peak at 565 nm and an emission peak at 610 nm, and is suitable alternative to PE-Texas Red, PE-eF610, PE-Alexa Fluor™ 610 or PE-CF®594. |
Images
|
Human peripheral blood lymphocytes were stained with CD49d (clone 9F10) PE/Dazzle™ 594 (filled histogram) or mouse IgG1, κ PE/Dazzle™ 594 isotype control (open histogram). |
Citations
| PMID 18941119 | ||
|---|---|---|
| PMID 20233972 | ||
| PMID 21765017 | ||
| Additional Sources |
|
Reviews & Ratings
PE-Dazzle 594 Excitation and Emission Spectra
$147.00
Supplier Page
Supplier Page
