Arginase 1 / PE / 14D2C43
Arginase 1 / PE / 14D2C43
Citations:
(4)
Product Details
| Supplier | BioLegend | |
|---|---|---|
| Catalog #: | 369703 (View supplier product page) | |
| Size | 25T | |
| Price | $153.00 | |
| Antigen | Arginase 1 | |
| Clone | 14D2C43 | |
| Host | Mouse | |
| Isotype | IgG2b κ | |
| Conjugate | PE | |
| Target Species | Human | |
| Applications | ICS | |
| Description | PE anti-human Arginase I |
About Arginase 1 and PE
| Arginase 1 | Arginase catalyzes the hydrolysis of arginine to ornithine and urea. At least two isoforms of mammalian arginase exist (types I and II) which differ in their tissue distribution, subcellular localization, immunologic crossreactivity and physiologic function. The type I isoform encoded by this gene, is a cytosolic enzyme and expressed predominantly in the liver as a component of the urea cycle. Inherited deficiency of this enzyme results in argininemia, an autosomal recessive disorder characterized by hyperammonemia. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011] | |
|---|---|---|
| PE | Phycoerythrin (PE, R-PE) is a red-emitting fluorescent protein-chromophore complex that can be excited the 488-nm blue, 532-nm green, or 561-nm yellow-green laser with increasing efficiency and captured with a 586/14 nm bandpass filter. PE has an excitation peak at 565 nm and an emission peak at 578 nm. PE is 240kD in size and has an extinction coefficient of ~2x10^6 which makes it one of the brightest fluorophores available and a potent donor upon which to build tandem fluorophores with longer Stoke's Shifts. |
Images
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Human peripheral blood was surface stained with CD15 APC and CD16 Pacific Blue™, fixed, permeabilized, and then intracellularly stained with Arginase I (clone 14D2C43) PE (filled histogram) or mouse IgG2b, κ PE isotype control (open histogram). Histogram was gated on the neutrophil (CD15+CD16+) population. |
Citations
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PE Excitation and Emission Spectra
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