FluoroFinder

	Supplier	Absolute Antibody
	Catalog #:	Ab00298-23.0-pe/cy7 (View supplier product page)
	Size	200 μg
	Price
	Antigen	SNAP25
	Clone	SP12
	Host	Rabbit
	Isotype	IgG
	Conjugate	PE-Cy7
	Target Species	Bovine, Feline, Guinea Pig, Hamster, Human, Mouse, Porcine, Rat
	Applications	IHC, WB, IF, ELISA
	Description	Anti-SNAP-25 [SP12]

	SNAP25	Synaptic vesicle membrane docking and fusion is mediated by SNAREs (soluble N-ethylmaleimide-sensitive factor attachment protein receptors) located on the vesicle membrane (v-SNAREs) and the target membrane (t-SNAREs). The assembled v-SNARE/t-SNARE complex consists of a bundle of four helices, one of which is supplied by v-SNARE and the other three by t-SNARE. For t-SNAREs on the plasma membrane, the protein syntaxin supplies one helix and the protein encoded by this gene contributes the other two. Therefore, this gene product is a presynaptic plasma membrane protein involved in the regulation of neurotransmitter release. Two alternative transcript variants encoding different protein isoforms have been described for this gene. [provided by RefSeq, Jul 2008]
	PE-Cy7	PE-Cyanine®7 (PE-Cy7, RPE-Cy7) is a far red-emitting tandem fluorophore that combines phycoerythrin (PE) and Cy7. The donor molecule, PE can be excited by the 488-nm blue, 532-nm green, or 561-nm yellow-green laser and and transfers energy to the acceptor molecule, Cy7, which emits light that can be captured with a 780/60 nm bandpass filter. PE-CY7 has an excitation peak at 565 nm and an emission peak at 778 nm, and is a suitable alternative to PE-Vio®770 (Miltenyi) and cFluor BYG781 (Cytek).

	Additional Sources

SNAP25 / PE-Cy7 / SP12