FluoroFinder

	Supplier	Absolute Antibody
	Catalog #:	Ab00279-13.0-pe/cy7 (View supplier product page)
	Size	200 μg
	Price
	Antigen	EGF Receptor
	Clone	C225 (Cetuximab)
	Host	Human
	Isotype	IgG4
	Conjugate	PE-Cy7
	Target Species	Human
	Applications	Block, FC
	Description	Anti-EGFR [C225 (Cetuximab)]

	EGF Receptor	The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor, thus inducing receptor dimerization and tyrosine autophosphorylation leading to cell proliferation. Mutations in this gene are associated with lung cancer. EGFR is a component of the cytokine storm which contributes to a severe form of Coronavirus Disease 2019 (COVID-19) resulting from infection with severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2). [provided by RefSeq, Jul 2020]
	PE-Cy7	PE-Cyanine®7 (PE-Cy7, RPE-Cy7) is a far red-emitting tandem fluorophore that combines phycoerythrin (PE) and Cy7. The donor molecule, PE can be excited by the 488-nm blue, 532-nm green, or 561-nm yellow-green laser and and transfers energy to the acceptor molecule, Cy7, which emits light that can be captured with a 780/60 nm bandpass filter. PE-CY7 has an excitation peak at 565 nm and an emission peak at 778 nm, and is a suitable alternative to PE-Vio®770 (Miltenyi) and cFluor BYG781 (Cytek).

	Additional Sources

EGF Receptor / PE-Cy7 / C225 (Cetuximab)